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Standard Cancer Drugs Do Little to Help those Suffering with Mesothelioma, However Genetic Therapy Offers a Hope

July 6th, 2009 by admin

Oncologists and other cancer doctors choose what course of treatment to prescribe with each patient. There are many options. There are no standard treatment option for pleural mesothelioma cancer patients. Mesotheliomas lack of agreed-upon treatment is due to low a treatment success rate, rareness, a high mortality rate and a small number of studies providing meaningful stats.

While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) All three methods have problems. Mesothelioma patients treated with traditional radiation therapy have not responded well to it. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.

The mesothelial tissue around the tumor is removed by surgery. This surgery is extensive and it is not clear how much the patient benefits. The usual chemotherapy cocktails effective on other cancers are not effective on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. Similar to radiation, focus in research is focusing on treating the physical location of the tumor with emphasis on the pleural cavity.

The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. These techniques include a biologic therapy called the agent interleukin 2 and anti-angiogenesis drugs like thalidomide. The new drug pemetrexed (brand name Alimta) has shown good results in extending life with mesotheliomas..

Before acting, oncologists review the stage of mesothelioma, position of the tumor, and age and health status of the patient. Theres also photodynamic therapy and gene therapy ” two far-out new ways of attacking cancer. Mesothelioma patients sometimes become involved in clinical trials in this area, and see benefits.

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